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Pathology

Parkinson’s Disease Patients at Higher Risk for Melanoma

Study finds that people with Parkinson’s disease have a much higher risk of the skin cancer melanoma, and vice versa. Physicians treating patients with one disease should be vigilant for signs of the other in order to achieve early diagnosis and treatment, and patients should be educated about the risk of developing the other illness. More...
24 Jul 2017
Image: A histopathology of a skin biopsy from a patient with amyloidosis. Protein clumps are in red (Photo courtesy of Professor Michael Polydefkis).

Nerve Biomarkers Found for Amyloid Polyneuropathy

A modified skin biopsy that hastens the earlier diagnosis of an inherited and progressively fatal nerve disease has been described that seems to offer a clearer view of the disorder's severity and progression. More...
19 Jul 2017
Image: A scanning electron micrograph (SEM) of ovarian cancer cells (Photo courtesy of SPL).

MALDI-TOF-MS Analysis Identifies Ovarian Cancer Patterns

Ovarian cancer (OC) is one of the leading causes of death among all gynecological malignancies and as there are no early specific symptoms, OC is diagnosed in advanced clinical stages in more than 70% cases when, despite appropriate treatment, five-year survival rate drops to 30%. More...
18 Jul 2017
Image: A scientist adjusting the versatile light-sheet microscope that can provide surgeons with real-time pathology data to guide cancer-removal surgeries and can also non-destructively examine tumor biopsies in 3D (Photo courtesy of Mark Stone/University of Washington).

Novel Microscope Scans Tumors and Examines Biopsies

Current pathology techniques involve processing and staining tissue samples, embedding them in wax blocks, slicing them thinly, mounting them on slides, staining them, and then viewing these two-dimensional tissue sections with traditional microscopes, which can take days. More...
12 Jul 2017
Image: A new study shows that so-called “liquid biopsies” - blood tests that detect circulating tumor DNA (ctDNA) - may not only sound an early alert that a treatment’s effect is diminishing, but may also help explain why and sometimes offer clues about what to do next (Photo courtesy of Massachusetts General Hospital).

Liquid Biopsy Blood Tests Detect CtDNA

The so-called “liquid biopsies” blood tests that detect circulating tumor DNA (ctDNA), may not only sound an early alert that a treatment’s effect is diminishing, but may also help explain why, and sometimes offering clues about what to do next. More...
12 Jul 2017
Image: Blood samples being prepared for the Three-In-One Blood Test that predicts a patient\'s response to PARP inhibitors (Photo courtesy of The Institute of Cancer Research).

Three-In-One Blood Test Could Fuel Personalized Prostate Cancer Treatment

A three-in-one blood test has been developed that can predict a patient's response to Poly ADP ribose polymerase (PARP) inhibitors, as well as how well the drugs may impact survival, and how likely patients are to develop drug resistance. More...
06 Jul 2017
Image: A health professional takes blood from a patient for the carcinoembryonic antigen (CEA) test (Photo courtesy of Mayo Clinic).

Simple Test Improves Treatment for Colon Cancer Patients

Colorectal cancer is the fourth most common cancer in the USA and the second deadliest. There are four primary stages of colon cancer. Generally, with stage 2, the cancer has not spread to nearby lymph nodes or distant organs but has grown into or through the wall of the colon. More...
06 Jul 2017
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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