Features Partner Sites Information LinkXpress hp
Sign In
Advertise with Us
LGC Clinical Diagnostics

Download Mobile App




Blood-Based Molecular Test Improves Early Detection of Colorectal Cancer

By LabMedica International staff writers
Posted on 03 Mar 2015
A convenient blood test can be ordered by a physician during a routine medical checkup to accurately and reliably detect both adenomatous polyps and early stages of colorectal cancer.

Mononuclear cells (PBMCs) are particularly responsive to growing adenomatous polyps and colorectal carcinomas and determining the expression of 29 genes in PBMCs provides a telltale sign of the early stages of colorectal cancer.

The new molecular blood test for the detection of colorectal cancer and precancerous lesions such as adenomatous polyps is called Colox; it has been approved for sale in Europe, and has been launched commercially in Switzerland. More...
Colox is available as a Laboratory Developed Test and is highly suited to standard medical laboratory workflow and is also available as a Conformité Européenne (CE) registered kit.

The Colox test was originally developed by Diagnoplex SA (Epalinges, Switzerland) and represents a new generation of cancer diagnostic tests based on the response of the organism against the tumor. The molecular diagnostics company Novigenix SA (Epalinges, Switzerland) announced it has acquired Colox. Gene expression data are interpreted by Novigenix's proprietary algorithm which generates the Colox test report. This algorithm is based on classifier combinations derived from mathematical analytical methods that underpin the reliability of the test.

Colox has been tested in a multicenter clinical study at the Centre Hospitalier Universitaire Vaudois (Lausanne, Switzerland). Gian Dorta, MD, a professor who led the study said, “Colox accurately and reliably detects both adenomatous polyps and early stages of colorectal cancer with a convenient blood test that can be ordered as part of a routine medical checkup. As a result Colox has the potential to dramatically increase screening compliance and reduce the mortality rate from this deadly disease.”

Brian B Hashemi, PhD MBA, Executive Chairman of Novigenix, said, “Our vision is to support physicians and the healthcare community in significantly reducing cancer mortality through the early diagnosis and intervention of colorectal cancer. We are committed to making Colox available to physicians and patients across Switzerland, followed by expansion in other European countries. Colorectal cancer is today the third most lethal cancer, but can be largely prevented if detected early by an accurate, reliable, and convenient test such as Colox.”

Related Links:
Diagnoplex SA 
Novigenix SA
Centre Hospitalier Universitaire 



Platinum Member
Xylazine Immunoassay Test
Xylazine ELISA
Verification Panels for Assay Development & QC
Seroconversion Panels
Anti-Cyclic Citrullinated Peptide Test
GPP-100 Anti-CCP Kit
Gold Member
High-Density Lipoprotein Containing Cholesterol Assay
HDL-c direct FS
Read the full article by registering today, it's FREE! It's Free!
Register now for FREE to LabMedica.com and get access to news and events that shape the world of Clinical Laboratory Medicine.
  • Free digital version edition of LabMedica International sent by email on regular basis
  • Free print version of LabMedica International magazine (available only outside USA and Canada).
  • Free and unlimited access to back issues of LabMedica International in digital format
  • Free LabMedica International Newsletter sent every week containing the latest news
  • Free breaking news sent via email
  • Free access to Events Calendar
  • Free access to LinkXpress new product services
  • REGISTRATION IS FREE AND EASY!
Click here to Register








Channels

Clinical Chemistry

view channel
Image: QIP-MS could predict and detect myeloma relapse earlier compared to currently used techniques (Photo courtesy of Adobe Stock)

Mass Spectrometry-Based Monitoring Technique to Predict and Identify Early Myeloma Relapse

Myeloma, a type of cancer that affects the bone marrow, is currently incurable, though many patients can live for over 10 years after diagnosis. However, around 1 in 5 individuals with myeloma have a high-risk... Read more

Immunology

view channel
Image: The cancer stem cell test can accurately choose more effective treatments (Photo courtesy of University of Cincinnati)

Stem Cell Test Predicts Treatment Outcome for Patients with Platinum-Resistant Ovarian Cancer

Epithelial ovarian cancer frequently responds to chemotherapy initially, but eventually, the tumor develops resistance to the therapy, leading to regrowth. This resistance is partially due to the activation... Read more

Technology

view channel
Image: Ziyang Wang and Shengxi Huang have developed a tool that enables precise insights into viral proteins and brain disease markers (Photo courtesy of Jeff Fitlow/Rice University)

Light Signature Algorithm to Enable Faster and More Precise Medical Diagnoses

Every material or molecule interacts with light in a unique way, creating a distinct pattern, much like a fingerprint. Optical spectroscopy, which involves shining a laser on a material and observing how... Read more

Industry

view channel
Image: The collaboration aims to leverage Oxford Nanopore\'s sequencing platform and Cepheid\'s GeneXpert system to advance the field of sequencing for infectious diseases (Photo courtesy of Cepheid)

Cepheid and Oxford Nanopore Technologies Partner on Advancing Automated Sequencing-Based Solutions

Cepheid (Sunnyvale, CA, USA), a leading molecular diagnostics company, and Oxford Nanopore Technologies (Oxford, UK), the company behind a new generation of sequencing-based molecular analysis technologies,... Read more
Copyright © 2000-2025 Globetech Media. All rights reserved.