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Pathology

Image: Lipid-laden macrophages found in patients with vaping-related respiratory illness. Oily lipids are stained red (Photo courtesy of Andrew Hansen, MD, Jordan Valley Medical Center).

Vaping Illness Characterized by Lipid-Laden Cells in Lungs

Lung scans from patients with vaping illness look like a serious viral or bacterial pneumonia, but those tests come back negative. Instead, diagnosis has been based on exclusion of known causes of similar respiratory illnesses combined with knowing the patient has a history of vaping. More...
17 Sep 2019
Image: The i-STAT Alinity system integrates with-patient testing directly into the patient-care pathway, accelerating time to treatment, improving quality and increasing access to care (Photo courtesy of Abbott).

New Blood Test Helps Detect Brain Injury in Minutes

After traumatic brain injury (TBI), plasma concentration of glial fibrillary acidic protein (GFAP) correlates with intracranial injury visible on computerized axial tomography (CT) scan. Some patients with suspected TBI with normal CT findings show pathology on magnetic resonance imaging (MRI). More...
11 Sep 2019

Gout Increases Risk of Advanced Chronic Kidney Disease

Chronic kidney disease (CKD) is a major public health epidemic, with at least 1 in 10 individuals having some degree of kidney impairment, contributing substantially to adverse clinical and economic outcomes. More...
11 Sep 2019
Image: A major new study on the association between blood glucose levels, including HbA1c, and risks of organ impairment in people with type 1 diabetes can make a vital contribution to diabetes care (Photo courtesy of HealthEngine).

Blood Sugar Levels Affect Risks in Type 1 Diabetes

Type 1 diabetes is the predominant form of diabetes diagnosed in childhood and is characterized by increased blood glucose levels resulting from insulin deficiency. More...
11 Sep 2019
Image: A diagram illustrating the combined use of bioorthogonal ligation (i.e., the reaction between Tz and TCO) and disulfide cleavage–driven by DTT to enable capture and release of CTCs using Click Chips (Photo courtesy of University of California, Los Angeles).

CTC Purification Enables Identification of Cancer-Linked Genetic Arrangements

The use of circulating tumor cells (CTCs) as a surrogate tumor source for molecular profiling of disease offers a potential noninvasive diagnostic solution for understanding underlying tumor biology, guiding treatment interventions, and monitoring disease progression. More...
29 Aug 2019
Image: A photomicrograph showing numerous completely sclerotic glomeruli and severe chronic tubulointerstitial nephritis from a patient with end-stage kidney disease (Photo courtesy of Dr. Jian-Hua Qiao, MD, FCAP).

Proteinuria Contributes to Greater CKD Progression Risk in Men

Older men with chronic kidney disease had a 50% increased risk for progression to end-stage kidney disease (ESKD) compared with women and this may be the result of higher levels of proteinuria. More...
29 Aug 2019
Image: A new study showed men with diabetes had a higher blood testosterone level than non-diabetic men (Photo courtesy of Diamed Diagnostical Center).

Hormone Levels of Diabetic Men Not Related to Prostate Cancer Risk

Diabetes mellitus (DM) is a group of metabolic disorders characterized by high blood sugar levels over a prolonged period and is conventionally associated with an increased risk of cancer; however, inverse associations of diabetes with prostate cancer are well described. More...
21 Aug 2019
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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