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Pathology

Image: Triple fecal immunochemical testing (FIT) surpasses single sigmoidoscopy in colorectal cancer (CRC) screening (Photo courtesy of Pinnacle Biolabs).

Triple FIT Surpasses Single Sigmoidoscopy in CRC Screening

Colorectal cancer (CRC) almost always develops from precancerous polyps (abnormal growths) in the colon or rectum. Screening tests can find precancerous polyps, so that they can be removed before they turn into cancer. Screening tests can also find colorectal cancer early, when treatment works best. More...
10 Dec 2020
Image: Histopathology of a cirrhotic liver.  High-density lipoprotein cholesterol predicts survival in cirrhotic patients with acute gastrointestinal bleeding (Photo courtesy of Loyola University Chicago).

HDL-Cholesterol Predicts Survival in Cirrhotic Patients with Gastrointestinal Bleeding

Liver cirrhosis is an important cause of morbidity and mortality as a consequence of continuous liver injuries. Acute gastrointestinal bleeding is a serious complication and critical clinical event in cirrhotic patients. Hepatitis B virus (HBV) is the leading cause of liver cirrhosis in China. More...
10 Dec 2020
Image: Appearance of a `false brush border` of Brachyspira pilosicoli cells attached by one cell end to the luminal surface of human colonic enterocytes in a patient diagnosed with human intestinal spirochetosis (Photo courtesy of David J. Hampson, PhD, DSc).

Specific Gut Bacterium Linked to Irritable Bowel Syndrome

The incidence of Irritable Bowel Syndrome (IBS) steeply increases following a gastroenteritis episode, suggesting a possible causative role for microbial perturbation. Gut microbiota composition studies overwhelmingly rely on fecal material. More...
08 Dec 2020
Image: An ELISA kit for measuring gastric inhibitory polypeptide (GIP) (Glucose-dependent insulinotropic polypeptide) (Incretin hormone) in human sera (Photo courtesy of RayBiotech Life).

Incretin Hormone Levels Linked to Arteriosclerosis

While existing evidence supports beneficial cardiovascular effects of glucagon-like peptide 1 (GLP-1), emerging studies suggest that glucose-dependent insulinotropic peptide (GIP) and/or signaling via the GIP receptor may have untoward cardiovascular effects. More...
30 Nov 2020
Image: IntelliSite Ultra-Fast Digital pathology slide scanner is designed to accommodate current histopathology needs for routine use in high volume labs and integrated pathology networks (Photo courtesy of Philips Digital Pathology Solutions).

Mitoses Counted with Digital Pathology in Breast Phyllodes Tumors

Phyllodes tumors (PTs) are a fibroepithelial tumor composed of an epithelial and a cellular stromal component. They may be considered benign, borderline, or malignant depending on histologic features including stromal cellularity, infiltration at the tumor's edge, and mitotic activity. More...
26 Nov 2020
Image: Histopathology of Guillain-Barré syndrome: Inflammation in peripheral nerve (Photo courtesy of Dimitri P. Agamanolis, MD).

Blood Biomarker Predicts Guillain-Barré Prognosis

Guillain-Barré syndrome (GBS) is a rare, autoimmune disorder in which a person’s own immune system damages the nerves, causing muscle weakness and sometimes paralysis. GBS can cause symptoms that last for a few weeks to several years. Most people recover fully, but some have permanent nerve damage. More...
25 Nov 2020
Image: Histological features of COVID-19 lungs (Photo courtesy of the University of Trieste).

COVID-19 Lung Damage Caused by Persistence of Abnormal Cells

Several uncertainties still relate to the involvement of other organs in COVID-19. Besides indirect multi-organ injury, a few reports have suggested the possibility of direct injury caused by viral replication in brain, heart and kidney. More...
19 Nov 2020
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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