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Microbiology

Image: The NEBNext ultra directional RNA library prep kit (Photo courtesy of New England Biolabs).

Nanopore Sequencing Enables Outbreak Field Surveillance

Outbreaks of fever of unknown origin start with nonspecific symptoms and case definition is only slowly developed and adapted, therefore, identifying the causative agent is crucial to ensure suitable treatment and control measures. More...
03 Oct 2018

Standalone HPV Testing Recommended for Cervical Cancer Screening

The number of deaths from cervical cancer in the USA has decreased substantially since the implementation of widespread cervical cancer screening and has declined from 2.8 to 2.3 deaths per 100,000 women from 2000 to 2015. More...
02 Oct 2018
Image: A single immunochromatography test for the triple independent identification of OXA-48-like, KPC and NDM carbapenemase on bacterial colony using the RESIST-3 O.K.N. assay (Photo courtesy of Coris BioConcept).

New Test Procedure Diagnoses Multi-Resistant Pathogens

Patients with bloodstream infections caused by gram-negative pathogens such as Escherichia coli (E. coli) have a high mortality rate. However, the infection has so far usually been treatable with antibiotics. More...
01 Oct 2018
Image: Auramine O stained Mycobacterium leprae in FFPE tissue section under ×40 objective of light-emitting diode fluorescence microscope A: Sample with high BI; B. Sample with low BI (Photo courtesy of Armauer Hansen Research Institute).

Molecular and Classical Methods Compared for Leprosy Diagnosis

Mycobacterium leprae is the causative agent of leprosy, a chronic granulomatous infectious disease affecting the skin and peripheral nerves. Leprosy manifests in various forms based on the immunological profiles and bacterial load in patients. More...
27 Sep 2018
Image: The SpinDx system (Photo courtesy of Sandia National Laboratories).

Integrated LAMP and Immunoassay Platform Detect Diarrheal Disease

The challenges of diagnosing infectious disease, especially in the developing world, and the shortcomings of available instrumentation have exposed the need for portable, easy-to-use diagnostic tools capable of detecting the wide range of causative microbes while operating in low resource settings. More...
26 Sep 2018
Image: The matrix-assisted laser desorption ionization–time of flight mass spectrometer (Photo courtesy of Bruker Daltonics).

MALDI-TOF MS Used to Identify Pythiosis

Pythiosis is a life-threatening infectious disease caused by the oomycete Pythium insidiosum. The disease has been increasingly reported worldwide and most patients with pythiosis undergo surgical removal of an infected organ. More...
25 Sep 2018
Image: Immunostaining of Helicobacter pylori infection in the small intestine. The small spiral-curved shaped bacterium can be seen clearly using a ×100 oil objective under the microscope (Photo courtesy of BioCare Medical).

Tumor Markers Associated with H. Pylori Infection

Helicobacter pylori infection is a major cause of several cancers such as gastric, pancreatic and lung. The relationship between H. pylori and tumor markers continues to remain unclear. As one of the leading causes of morbidity and mortality globally, cancer represents a major detrimental public health problem worldwide. More...
19 Sep 2018
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The LabMedica Microbiology channel provides the latest news in the fields of epidemiology, bacteriology, virology, and parasitology, all viewed from the unique perspective of Laboratory Medicine.
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