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Immunology

Image: The BinaxNOW Legionella Urinary Antigen Card. Accurate. Rapid identification of Legionnaires` disease caused by Legionella pneumophila serogroup 1 with an easy-to-use technology (Photo courtesy of Abbott).

Urinary Antigen Test Kit Evaluated for Diagnosing Legionella Pneumonia

Legionellosis is caused by bacteria called Legionella. The disease has two different forms. Legionnaires’ disease is the more severe form of infection that causes pneumonia. Pontiac fever is caused by the same bacteria, but is a milder illness without pneumonia. More...
24 Feb 2021
Image: Glioblastoma omics highlights informative tumor features, immune subtypes (Photo courtesy of Washington University in St. Louis).

Proteogenomic And Metabolomic Studies Characterize Human Glioblastoma

Glioblastoma (GBM) is an aggressive type of cancer that can occur in the brain or spinal cord. Glioblastoma forms from cells called astrocytes that support nerve cells. Glioblastoma can occur at any age, but tends to occur more often in older adults. It can cause worsening headaches, nausea, vomiting and seizures. More...
23 Feb 2021
Image: T cell response in patients recovered from COVID-19 has been profiled using ImmunoScape TargetScape assay (Photo courtesy of The Scientist).

T Cell Response Profiled in COVID-19 Patients

The clinical spectrum of SARS-CoV-2 infection is highly variable, spanning from asymptomatic or subclinical infection, to severe or fatal disease. Characterization of the immune response to SARS-CoV-2 is urgently needed in order to better inform more effective treatment strategies, including antivirals and rationally designed vaccines. More...
22 Feb 2021
Image: The Z2 Coulter Counter Analyzer can be used to analyze virtually any cell type and species variation (Photo courtesy of Beckman Coulter).

Biomarker Predicts Pancreatic Cancer Patients’ Response to CD40 Immunotherapy

Pancreatic ductal adenocarcinoma (PDAC) is the most common type of pancreatic cancer and currently the third leading cause of cancer deaths in the USA. Despite the fact that it only accounts for about 3% of new cancer cases, it is responsible for more than 7% of all cancer deaths, and only10% of patients survive five years with the disease. More...
17 Feb 2021
Image: An association of epileptic and non-epileptic seizures and changes in circulating plasma proteins is linked to neuroinflammation (Photo courtesy of Evogen, Inc).

Blood Test Distinguishes Epileptic Seizures From PNES

Epilepsy is a central nervous system (neurological) disorder in which brain activity becomes abnormal, causing seizures or periods of unusual behavior, sensations, and sometimes loss of awareness. Epilepsy affects both males and females of all races, ethnic backgrounds and ages. More...
16 Feb 2021
Image: The Technothrombin TGA is a thrombin generation assay (TGA) based on monitoring the formation of thrombin by means of a fluorogenic substrate upon activation of the coagulation cascade by tissue factor (Photo courtesy of Technoclone).

TFP Inhibitor Levels Elevated in Bleeding Tendency Patients

Mild to moderate bleeding disorders (MBDs) are characterized by symptoms such as epistaxis, easy bruising, or menorrhagia, but bleeding can also be severe under certain circumstances such as hemorrhage after surgery or birth. More...
11 Feb 2021
Image: Inter-α-inhibitor heavy chain 4 (ITIH4) inhibits proteases in the innate immune system via novel inhibitory mechanism (Photo courtesy of Rasmus Kjeldsen Jensen, PhD).

New Control Mechanism Discovered in Innate Immune System

Proteases are enzymes that cleave other proteins. Most often, proteases occur in cascade networks, where a particular event triggers a chain reaction in which several proteases cleave and thereby activate each other. Most well-known is probably the coagulation cascade, which causes clotting of our blood when a vessel is punctured. More...
11 Feb 2021
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.
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