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Immunology

Image: The Elecys S100 Assay, an electro-chemiluminescence immunoassay (ECLIA) for the in vitro quantitative determination of S100 in human serum (Photo courtesy of Roche Diagnostics)

Plasma-Based S100B Testing for Management of Traumatic Brain Injury

Traumatic brain injury (TBI) usually results from a violent blow or jolt to the head or body. An object that penetrates brain tissue, such as a bullet or shattered piece of skull, also can cause traumatic brain injury. Mild traumatic brain injury may affect the brain cells temporarily. More...
24 May 2021
Image: Schematic diagram of How Human Microbiota Flagellins Drive Adaptive Immune Responses in Crohn’s Disease (Photo courtesy of University of Alabama at Birmingham)

Human Microbiota Flagellins Drive Adaptive Immune Responses in Crohn’s Disease

Crohn's disease and ulcerative colitis, another type of inflammatory bowel disease (IBD), are characterized by dysregulated adaptive immune responses to the microbiota in genetically susceptible individuals, but the human specificity of these responses had so far been largely undefined. More...
20 May 2021
Image: Photomicrograph of Mycobacterium tuberculosis - Ziehl-Neelsen Acid-Fast Stains bacteria red (Photo courtesy of Rockefeller University)

Potential Immune Markers Found for Active Tuberculosis

Tuberculosis (TB) is an infectious disease usually caused by Mycobacterium tuberculosis (MTB) bacteria. Tuberculosis generally affects the lungs, but can also affect other parts of the body. Most infections show no symptoms, in which case it is known as latent tuberculosis. About 10% of latent infections progress to active disease which, if left untreated, kills about half of those affected. More...
18 May 2021
Image: Multiomic prediction of time to labor from biomarkers in maternal blood (Photo courtesy of STELZER ET AL.)

Maternal Multiomic Changes Could Predict Onset of Labor

Currently, predictions of when labor will start are imprecise and based on gestational age and an average pregnancy length of 40 weeks, even though the onset of labor between week 37 and 42 of pregnancy is considered normal. Having a better idea of when labor may arrive could help with planning and managing medical concerns like fetal lung maturation. More...
18 May 2021
Image: BinaxNOW COVID-19 Ag Cards (Photo courtesy of Abbott Laboratories)

Serial SARS-CoV-2 Rapid Antigen Testing Evaluated During Outbreaks

Serial, facility-wide testing for SARS-CoV-2 can help identify cases in outbreak settings, allowing for rapid implementation of transmission-based precautions and infection prevention and control strategies. More...
13 May 2021
Image: The Capillarys 3 TERA is an automated analyzer based on capillary zone electrophoresis and UV detection for the quantitative analysis of Hba1c, proteins (serum and urine), immunotyping (serum and urine), and carbohydrate deficient transferrin (Photo courtesy of Sebia)

Gel and Capillary Electrophoresis Compared for Human Proteins

The electrophoresis of serum proteins remains a laboratory cornerstone for the diagnosis and monitoring of patients with plasma cell disorders, such as monoclonal gammopathy of undetermined significance, multiple myeloma, Waldenström macroglobulinemia, and AL amyloidosis. More...
12 May 2021
Image: The HISCL-5000 is a fully automated immunoassay system designed for fast, highly sensitive and reliable immunoassay testing (Photo courtesy of Sysmex)

Developed Immunoassay Predicts Benefits of Anti-PD-1 Therapy in NSCLC

Lung cancer is the most common cause of cancer-related deaths worldwide. However, current targeted therapies and immunotherapies have gradually improved patient survival. Anti-programmed cell death-1 (PD-1) antibodies (Abs) are key drugs in non-small-cell lung cancer treatment; however, clinical benefits with anti-PD-1 monotherapy are limited. More...
12 May 2021
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.
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