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Clinical Chemistry

Image: The Genetic Screen Processor (GSP) is a high throughput batch analyzer intended for quantitative or qualitative measurement of neonatal screening samples on 96-well microplates (Photo courtesy of PerkinElmer)

Cord Blood and Filter Paper Screening Compared for Congenital Hypothyroidism

The most prevalent predisposing factor to intellectual disability is congenital hypothyroidism (CH), which is referred to the deficiency in thyroid hormone since birth. It could be either transient or persistent deficiency. Persistent deficiency of thyroid hormone requires life-long thyroid hormone replacement. This state is known as permanent congenital hypothyroidism. More...
15 Dec 2021
Image: The Vantera Clinical Analyzer can identify and quantify concentrations of choline using NMR spectroscopy (Photo courtesy of American Association for Clinical Chemistry)

Serum and Plasma Choline Quantified by Clinical NMR- Analyzer

Gut microbiome-related metabolites, like trimethylamine-N-oxide (TMAO), betaine and choline are increasingly recognized as contributors to, as well as markers of, cardiometabolic and other chronic diseases. Gut microbiome mediated metabolism of phosphatidylcholine leads to the production of choline, which is then metabolized to either trimethylamine (TMA) or betaine. More...
14 Dec 2021
Image: Apolipoprotein B–containing lipoproteins are associated with risk of myocardial infarction in individuals with and without atherosclerosis (Photo courtesy of the Cardiovascular Research Foundation)

Apolipoprotein B Singled Out as Heart Attack Risk Predictor

The selection of risk factors is based on what makes a highly significant independent contribution to predicting risk. Age, sex, smoking, systolic blood pressure and total cholesterol are well known to be important. Also, diabetes and left ventricular hypertrophy increase risk as does a previous stroke or heart attack. More...
09 Dec 2021
Image: The UniCel DxH 800 Coulter Cellular Analysis System (Photo courtesy of Beckman Coulter)

Monocyte Distribution Width Predicts Sepsis in Critically Ill Patients

Sepsis has been reported as a major cause of increased morbidity, length of stay and mortality among patients hospitalized in Intensive Care Units (ICUs) for any cause. The survival of patients developing sepsis in the ICU is strictly related to an early diagnosis, as well as a prompt start of appropriate medical interventions. More...
06 Dec 2021
Image: Illustration is of the Vertical Auto Profile (VAP) Lipid test with clear demarcation of the different lipoprotein classes and subclasses. (Photo courtesy of VAP Diagnostics Laboratory)

Lipoprotein(a) Concentrations Correlate With LDL-C in Diabetic Children

Cardiovascular disease (CVD) is a significant cause of mortality in those with diabetes. Increased apolipoprotein B (apoB) and low-density lipoprotein cholesterol (LDL-C) have been shown in pediatric patients with diabetes with worsening glycemic control. More...
30 Nov 2021
Image: DxU Iris Workcell (Photo courtesy of Beckman Coulter, Inc.)

Beckman Coulter Launches Automated, High-Throughput DxU Iris Urinalysis Solution in Europe

Beckman Coulter, Inc. (Brea, CA, USA) has announced the European launch of the DxU Iris Workcell, a fully-automated system that streamlines urinalysis workflow and reduces manual microscopy. More...
30 Nov 2021
Image: Atellica Solution (Photo courtesy of Siemens Healthineers)

Siemens Introduces New Intelligent, Integrated IVD Solutions Virtually at EUROMEDLAB 2021

Siemens Healthineers (Erlangen, Germany) introduced new intelligent, integrated IVD solutions virtually at the XXIV IFCCEFLM European Congress of Clinical Chemistry and Laboratory Medicine (EuroMedLab Congress 2021). More...
29 Nov 2021
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.
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